Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the procedure of various myeloma. Its synthesis or review is important for making certain the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A critical compound during the synthesis of imatinib, a drug that targets distinct types of cancer, which include chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers for instance breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their research is vital for optimizing the production method and ensuring significant purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is used CAS NO. 155405-80-4 to treat breast cancer, and these intermediates are involved in its generation.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the therapy of breast cancer. Various intermediates help in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in treating cancers for example ovarian, breast, and lung most cancers.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the remedy of colorectal most cancers and smaller mobile lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved in the synthesis of adamantane derivatives, which have different apps, together with antiviral properties.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for variety two diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, that are used in foodstuff, pharmaceutical, and industrial 5(10)-triene-3 programs.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication used to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).